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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXD4
All Species:
0.61
Human Site:
S321
Identified Species:
1.33
UniProt:
Q12950
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12950
NP_997188.2
439
47251
S321
R
E
A
D
A
S
L
S
A
L
R
V
S
C
K
Chimpanzee
Pan troglodytes
NP_001009014
413
45421
S296
P
A
P
F
P
C
C
S
P
H
L
V
L
S
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q60688
444
48029
E323
G
C
A
S
F
T
I
E
S
I
M
Q
G
V
T
Rat
Rattus norvegicus
Q63245
101
11924
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516678
728
77542
R453
F
S
I
E
S
I
M
R
G
N
K
A
E
G
G
Chicken
Gallus gallus
P79772
394
40977
L282
P
L
L
P
S
G
E
L
S
R
K
A
F
N
A
Frog
Xenopus laevis
Q9DEN4
371
40000
K262
P
S
S
E
L
T
R
K
A
F
S
S
Q
L
S
Zebra Danio
Brachydanio rerio
NP_571365
371
40457
N262
L
L
P
S
A
E
L
N
R
K
A
F
S
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02361
456
49036
A320
D
V
A
T
V
A
S
A
A
G
I
P
G
H
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496411
333
37274
K224
L
R
R
R
K
R
Y
K
K
N
S
D
T
Y
H
Sea Urchin
Strong. purpuratus
XP_001188749
401
43606
L288
N
G
A
L
S
S
L
L
S
A
G
I
T
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.6
N.A.
N.A.
N.A.
48.6
20.5
N.A.
33
38.2
34.8
32.7
N.A.
30.9
N.A.
31.2
34.8
Protein Similarity:
100
83.1
N.A.
N.A.
N.A.
55.6
21.6
N.A.
41.4
46.7
46.4
45.3
N.A.
44
N.A.
43.2
44.8
P-Site Identity:
100
13.3
N.A.
N.A.
N.A.
6.6
0
N.A.
0
0
6.6
20
N.A.
13.3
N.A.
0
20
P-Site Similarity:
100
13.3
N.A.
N.A.
N.A.
33.3
0
N.A.
26.6
20
26.6
33.3
N.A.
33.3
N.A.
6.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
37
0
19
10
0
10
28
10
10
19
0
0
19
% A
% Cys:
0
10
0
0
0
10
10
0
0
0
0
0
0
10
0
% C
% Asp:
10
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
10
0
19
0
10
10
10
0
0
0
0
10
0
0
% E
% Phe:
10
0
0
10
10
0
0
0
0
10
0
10
10
0
0
% F
% Gly:
10
10
0
0
0
10
0
0
10
10
10
0
19
19
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
10
% H
% Ile:
0
0
10
0
0
10
10
0
0
10
10
10
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
19
10
10
19
0
0
0
10
% K
% Leu:
19
19
10
10
10
0
28
19
0
10
10
0
10
10
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
10
0
19
0
0
0
10
0
% N
% Pro:
28
0
19
10
10
0
0
0
10
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% Q
% Arg:
10
10
10
10
0
10
10
10
10
10
10
0
0
0
10
% R
% Ser:
0
19
10
19
28
19
10
19
28
0
19
10
19
19
10
% S
% Thr:
0
0
0
10
0
19
0
0
0
0
0
0
19
0
10
% T
% Val:
0
10
0
0
10
0
0
0
0
0
0
19
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _